Louis-Antoine Ranvier
(2 October 1835 – 22 March 1922)
was a French physician, pathologist, anatomist and histologist, who discovered the nodes of Ranvier, regularly spaced discontinuities of the myelin sheath, occurring at varying intervals along the length of a nerve fiber.
Ranvier was born and studied medicine at Lyon, graduating in 1865. He founded a small private research laboratory with Victor André Cornil, and together they offered a course in histology to medical students. They also wrote together an influential textbook on histopathology. In 1867, Ranvier entered the Collège de France and worked as an assistant to Claude Bernard. In 1875, he was appointed to its chair of general anatomy.
In 1878, Ranvier discovered the
nodes which received his name. Other anatomical structures bearing his
name are the Merkel-Ranvier cells, melanocyte-like cells in the basal
layer of the epidermis that contain catecholamine granules; and
Ranvier's tactile disks, a special type of sensory nerve ending. In
1897, he founded the scientific journal Archives d'anatomie
microscopique with Edouard-Gérard Balbiani.
In the decade after World War I, MS research grew more sophisticated. Abnormalities in spinal fluid were noted for the first time in 1919, though their significance was a puzzle. Myelin, which had been discovered in 1878 by Dr. Louis Ranvier, was studied intensively under the microscope and the cells that make myelin (the oligodendrocytes) were discovered in 1928.
was a French physician, pathologist, anatomist and histologist, who discovered the nodes of Ranvier, regularly spaced discontinuities of the myelin sheath, occurring at varying intervals along the length of a nerve fiber.
Ranvier was born and studied medicine at Lyon, graduating in 1865. He founded a small private research laboratory with Victor André Cornil, and together they offered a course in histology to medical students. They also wrote together an influential textbook on histopathology. In 1867, Ranvier entered the Collège de France and worked as an assistant to Claude Bernard. In 1875, he was appointed to its chair of general anatomy.
In the decade after World War I, MS research grew more sophisticated. Abnormalities in spinal fluid were noted for the first time in 1919, though their significance was a puzzle. Myelin, which had been discovered in 1878 by Dr. Louis Ranvier, was studied intensively under the microscope and the cells that make myelin (the oligodendrocytes) were discovered in 1928.
No comments:
Post a Comment